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  Dendritic Cell Therapy  
 
RC: Dendritic Cell therapy represents a new and most promising immunotherapeutic approach to the treatment of cancer. As Dr. Eyre, VP of Research at the AMA commented: it is perhaps premature to make a great deal out of it but, patients' responses are far out of proportion to anything that any current therapy could do. DC Therapy is heroretically sound and has a clinical track record of a 20-30% response rate even in heavily pretreated advanced cancers of all types (solid tumors, hematologic cancers, brain and childhood tumors included). It is not toxic but requires careful logistic planning. We have routinely recommended and helped patients using DC therapy since 2003 in collaboration with the Institute of Tumortheray in Germany, and interested patients should visit www.dendritic.info for more information or otherwise contact us.
 
 

The National Cancer Institute has a very concise primer on Treating and Preventing Cancer with Vaccines on their site.

Dendritic Cells (I): Biological functions ” and “ Dendritic Cells (II) Role and therapeutic implications in cancer ” by S. Satthaporn and O. Eremin of the U. of Nottingham and Lincoln County Hospital, UK as published in J. of the Royal College Surgeons, Edinb.
46:9-20 and 159-167,2001.

Clinical Applications of Dendritic Cell Cancer Vaccines ” by Dr. Joseph Barr of the U. of Pittsburgh Cancer Institute, Pittsburgh, PA USA in The Oncologist 4(2): 140-144, 1999.

Also, a slide show / lecture presentation by Dr. Michael Morse on “ Current Status of Dendritic-Cell Vaccines ” is available on the Medscape site from WebMD as part of an educational session on “Therapeutic Cancer Vaccines: Targeting the Future of Cancer Treatment” but requires registration to enter the site.

Abstracts of recent reviews on Pubmed include articles by IG Schmidt-Wolf et al. on “ Dendritic Cell, the immunotherapeutic cell for cancer ”, TL Whiteside and C Odous from U. of Pittsburgh Cancer Institute on “ Dendritic cell biology and cancer therapy ”, EM Hersh et al. on “ Clinical Applications of dendritic cell vaccination in the treatment of cancer

For information on treatment centers and clinical trials, refer to www.dendritic.info.